Welcome to The First Descendant Mutant Cell overview page. Mutant Cells are special enhancements equipped in Mutant Cell Slots. Activating the slot works like a normal node and does not consume Arche Tuning. After activation, each slot must be unlocked once using 100 Fission Accelerants. Unlocking applies to all loadouts for that Descendant Group. Fission Accelerants and ARC Genetic Scissors (used for extraction) are both obtained by defeating Sigma Sector Commanders on Normal or High-risk. Equipping Mutant Cells is loadout-specific. Each loadout tracks its own equipped cells. Every slot has a Socket Type, and only Mutant Cells with the matching type can be slotted. Overriding a Mutant Cell with another one destroys the original, but has no cost. Extraction preserves the Mutant Cell and sends it to your inventory but costs 100 ARC Genetic Scissors. Resetting slots or Arche Tuning does not remove equipped Mutant Cells, but if the slot is reset, its effects won’t apply until reactivated. Mutant Cells are obtained from Spoils Boxes, which you open and manually choose a cell from. Spoils Boxes drop from Sigma Sector Missions: High-risk: 5% chance Normal: 2.5% chance Also a low chance drop from 400% Infiltration Operation commanders. High-risk: 5% chance Normal: 2.5% chance Also a low chance drop from 400% Infiltration Operation commanders. Mutant Cells Database for The First Descendant